Learn more and find a better solution for multiple sclerosis treatment with top experts. Visit our Online Brain Expert Center at
https://diagnosticdetectives.com/expe...
Exclusive interview / Dr. Anton Titov MD and Professor Dr. Paul Matthews, leading multiple sclerosis neurologist, neurodegeneration, brain imaging MRI, functional MRI, PET expert and precision medicine specialist.
Precision pharmacology. You led multiple sclerosis clinical program at the major pharmaceutical company, so you have very intricate knowledge of challenges in drug development process, and enormous costs that often prevent very promising basic research discoveries making the proverbial leap from bench to bedside. And you recently used the term Precision Pharmacology to describe human in vivo molecular imaging with positron emission tomography What is precision pharmacology? How it helps modern drug development process? And maybe you can provide an example of its use? Precision pharmacology is really a slight reworking of a very fundamental concept of pharmacology, which means we need to have a molecule that hits the right target, at the right time, and to the right level, and in the right patient. It's satisfying all of these criteria simultaneously. Now, the reason this is an important thought - it's kind of the flipside of precision medicine or personalized medicine. It's saying, "Let's think about the way in which we use drugs in the population as opposed to the way we treat patients". The two are intimately related but they're slightly different problems. Precision pharmacology is based around having measures that help us understand whether we've engaged the target, whether we've engaged it to the right extent, whether it's having the impact that we expected it to on pathology, and whether it's potentially benefiting that particular patient within a patient group. Precision pharmacology is something that in principle is part of the early [drug] development process to help us gain confidence through the development path that a medicine [drug] will have value when it comes to the other side [of development]. The reason it's important concept to move forward with, is it's a way of making sure that key traps in drug development are not run afoul of. It helps to also provide evidence of value of the medicine once it moves into the marketplace. And finally it helps to guide the personalized therapy or stratified therapy that would follow into the market by helping us begin to make clear hypotheses about who is the patient who will benefit and why... Professor Matthews, thank you very much for this very fascinating conversation about brain imaging, about multiple sclerosis, and the latest trends in development of treatment for multiple sclerosis as well as research use of functional MRI and other sophisticated MRI technologies that you are developing. We really appreciate your time, and I'm sure that it will be very interesting for us around the world to learn about the latest in brain imaging technologies and multiple sclerosis management. Thank you very much! - Thank you, Anton, it's nice speaking with you! - Thank you!
What is Precision Pharmacology? How It Helps to Personalize Treatment? (15) best treatment for damaged hair | |
| Likes | Dislikes |
| 6 views views | followers |
| Science & Technology | Upload TimePublished on 29 Jun 2018 |
Không có nhận xét nào:
Đăng nhận xét